DMT

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Facts

DMT is a white crystalline powder derived from certain plants found in Mexico, South America, and parts of Asia, such as Psychotria viridis. It is present in cohoba, a hallucinogenic drug derived from the seeds of Piptadenia peregrina.

People typically consume it in the following ways:

  • vaporized or smoked in a pipe
  • consumed orally in brews like ayahuasca
  • snorted or injected on rare occasions

The chemical root structure of DMT is similar to the anti-migraine drug sumatriptan, and it acts as a non-selective agonist at most or all of the serotonin receptors, particularly at the serotonin 5-HT2a receptor. Serotonin is a neurotransmitter that has a large effect on the majority of our brain cells.

There is some evidenceTrusted Source that the body also produces DMT endogenously. This means the body makes DMT, likely in the pineal gland of the brain.

A typical smoked doseTrusted Source of DMT is 40 to 100 milligramsTrusted Source (mg), and the drug begins working almost instantly. The effects peak and plateau for 2 to 5 minutes, and gradually drop off with the duration of effect totaling 30 to 60 minutes.

When consumed as a brew in the form of ayahuasca, the dose is between 0.6 – 0.85 mgTrusted Source for every kilogram of liquid. Effects begin within 60 minutes, peak after 90 minutes, and disappear in approximately 4 hours.

DMT street names

A number of slang terms exist for DMT:

  • Dimitri
  • Businessman’s trip
  • Businessman’s special
  • Fantasia
  • Forty-five-minute psychosis

DMT is a hallucinogenic tryptamine. DMT causes hallucinogenic effects that last for about 45 to 60 minutes.

As far as its psychoactive effects, people have described feeling like they’re traveling at warp speed through a tunnel of bright lights and shapes. Others describe having an out-of-body experience and feeling like they’ve changed into something else.

There are also some who report visiting other worlds and communicating with alien-like beings.

Some people also report a pretty rough comedown from DMT that leaves them feeling unsettled.

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